Asian Journal of Research in Cardiovascular Diseases

Superinfected Libman-Sacks Endocarditis Revealing a Systemic Lupus Erythematosus: Case Report with Review of the Literature

Charif H. *

Department of Cardiology, Ibn Rochd University Hospital, Casablanca, Morocco.

Haboub M.

Department of Cardiology, and Faculty of Medicine and Pharmacy, Ibn Rochd University Hospital, Casablanca, Hassan II University of Casablanca, Casablanca, Morocco.

Arous S.

Department of Cardiology, and Faculty of Medicine and Pharmacy, Ibn Rochd University Hospital, Casablanca, Hassan II University of Casablanca, Casablanca, Morocco.

Bennouna E.

Department of Cardiology, and Faculty of Medicine and Pharmacy, Ibn Rochd University Hospital, Casablanca, Hassan II University of Casablanca, Casablanca, Morocco.

Drighil A.

Department of Cardiology, and Faculty of Medicine and Pharmacy, Ibn Rochd University Hospital, Casablanca, Hassan II University of Casablanca, Casablanca, Morocco.

Azouzi L.

Department of Cardiology, and Faculty of Medicine and Pharmacy, Ibn Rochd University Hospital, Casablanca, Hassan II University of Casablanca, Casablanca, Morocco.

Habbal R.

Department of Cardiology, and Faculty of Medicine and Pharmacy, Ibn Rochd University Hospital, Casablanca, Hassan II University of Casablanca, Casablanca, Morocco.

*Author to whom correspondence should be addressed.

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Abstract

We present the case of isolated mitral regurgitation detected in a 24 years old patient who was presented to the cardiology department of Ibn Rochd University Hospital complaining of dyspnea on moderate exertion.  The present case report describes a 24 years-old Moroccan lady, single who were complaining of dyspnea on moderate exertion since 3 months. Parenteral probabilistic antibiotic therapy combining gentamicin (3 mg/kg/day) and ceftriaxone (2 g/d) was initiated and well followed. However, the clinical and biological course was stationary until the 7th day. This had motivated the realization of an immunological assessment which showed a high titer of anti-nuclear antibodies, positive native anti-DNA antibodies. Valvular abnormalities are often clinically silent, without significant valvular dysfunction. Valvular regurgitation is more common than stenosis, which is rare. Valvular dysfunction can result in cardiac failure. There is no consensual therapeutic protocol in the literature, hence the interest of multidisciplinary consultation meetings in which the place of the internist is essential.

Keywords: Anti-DNA antibodies, cardiology, anti-nuclear antibodies, libman-Sacks endocarditis

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