Asian Journal of Research in Cardiovascular Diseases <p style="text-align: justify;"><strong>Asian Journal of Research in Cardiovascular Diseases</strong>&nbsp;aims to publish&nbsp;high-quality&nbsp;papers (<a href="/index.php/AJRCD/general-guideline-for-authors">Click here for Types of paper</a>) in all areas of&nbsp;‘Cardiovascular Diseases’. This journal facilitates the research and wishes to publish papers as long as they are technically correct, scientifically motivated. The journal also encourages the submission of useful reports of negative results. This is a quality controlled,&nbsp;OPEN&nbsp;peer-reviewed, open access INTERNATIONAL journal.</p> <p style="text-align: justify;">&nbsp;</p> en-US (Asian Journal of Research in Cardiovascular Diseases) (Asian Journal of Research in Cardiovascular Diseases) Tue, 11 Aug 2020 09:53:05 +0000 OJS 60 Patent Ductus Arteriosus Closure by Paracetamol in a Critical Preterm Infant after Late Recanalization <p>Cyclooxygenase (COX) inhibitors form the first line of treatment for patent ductus arteriosus (PDA) in preterm neonates. However, their efficacy decreases with increasing postnatal age.&nbsp;Paracetamol can be used when COX inhibitors are contraindicated and in advanced postnatal age. We describe a late preterm neonate (five weeks postnatal age, 1550 g birth weight) with a hemodynamically significant PDA, where COX inhibitor therapy could not be initiated due to spontaneously perforated necrotizing enterocolitis that was treated surgically. At five weeks postnatal age and body weight of 1800 g intravenous paracetamol was started. Over a 3-day course, it led to complete closure of the PDA. With follow up three months after treatment, recanalization occurred but did not need further attention.</p> Abdelmonem Helal, Naif Alkhushi, M. O. Galal ##submission.copyrightStatement## Tue, 01 Sep 2020 00:00:00 +0000 A Case of Takotsubo Cardiomyopathy - How We Uncovered the Diagnosis <p><strong>Introduction: </strong>Takotsubo cardiomyopathy (TTC) is a stress-induced condition characterized by transient apical hypokinesia and is usually caused by stress-induced catecholamine release with toxic action that leads to stunning myocardium. The aim of this report is to present the female patient with takotsubo cardiomyopathy with&nbsp;&nbsp; clinical presentation, diagnosis, treatment and follow up of this condition. This patient has good prognosis with complete left ventricular systolic function recovery typically occurring within weeks.</p> <p><strong>Methods and Results:</strong> The patient was a 62 years old woman without any history of heart disease. She was admitted with chest pain and electrocardiography (ECG) with ST segment elevation in the precordial leads and troponins suggesting acute anterior myocardial infarction (MI). The urgent coronary angiography which is performed didn’t show obstructive coronary lesions. Echocardiography showed reduced left ventricle (LV) ejection fraction with LV apical ballooning and LV thrombus. Cardiac magnetic resonance imaging (MRI) showed localized hypokinesia of the mid septal segments and akinesis of all segments of the apex of the left ventricle and T2 hyperintesity consistent with myocardial transmural oedema in the same area with diffuse involvement. During the hospitalizasion patient was treated with single antiplatelet, anticoagulation therapy, diuretics, angiotensin-converting-enzyme inhibitors (ACE inhibitors) and beta blockers for treatment of heart failure reduced Ejection fraction (HFrEF). At 2 months follow up ECG was normal with reversal of symptoms and regression of wall motion abnormalities at echocardiography. According to investigation results, a diagnosis of takotsubo syndrome (TTS) was established.</p> <p><strong>Conclusion: </strong>Takotsubo cardiomyopathy often presents as an acute coronary syndrome with ST segment changes, as ST-segment elevation and/or T-wave inversion. Clinical presentation is characterized by acute coronary artery disease, in the absence of obstruction, verified by coronarography. Diagnostic methods are very important to make true decision of takotsubo cardiomyopathy and coronary angiography and cardiac MRI are the best.</p> V. Andova, M. Otljanska, H. Taravari, A. Jovkovski, N. Kostova, E. Caparoska, B. Zafirovska ##submission.copyrightStatement## Sat, 15 Aug 2020 00:00:00 +0000 Coronary Artery Aneurysm Revealed by an Acute Coronary Syndrome in a Patient with Systemic Lupus Erythematosus: A Case Report <p>Systemic lupus erythematosus is an inflammatory autoimmune disease of unknown etiology. The coronary lesions are extremely rare, particularly aneurysms.</p> <p>We report a case of a coronary aneurysm of a patient diagnosed with Systemic lupus erythematosus who showed up at the emergency department presenting, since for 4 hours, an acute retro-sternal chest pain radiating to his jaws.</p> <p>An electrocardiogram was performed urgently and showed an ST-elevation of 2mm in the infero-basal territories and right leads (V3r, V4r).</p> <p>The patient underwent coronary angiography which revealed an aneurysmal dilatation of the right coronary artery with multiple atherosclerotic aneurysms of different sizes with no thrombus visualized within the lumen.</p> <p>Coronary aneurysms are fatal and have potential complications that should be considered in the diagnostic of Cardiac involvement in Systemic lupus erythematosus since early detection might allow complete healing.</p> Hind Adnane, Saousan Serbout, El Ghali Med Benouna, Drighil Abdenasser, Azzouzi Leila, Habbal Rachida ##submission.copyrightStatement## Wed, 19 Aug 2020 00:00:00 +0000 Perceived Cardiovascular Disease Risk Factors among Adolescents in Riyadh, Saudi Arabia <p><strong>Objectives:</strong> The aim of this study is to assess the level of knowledge and perceivement of cardiovascular risk factors among male adolescent students and the practiced healthy lifestyle.</p> <p><strong>Methods:</strong> A cross-sectional multistage study targeted adolescent male students from public secondary schools in Riyadh, Saudi Arabia. They were surveyed by using a self-administered questionnaire. The participants were categorized as knowledgeable and perceiving the cardiovascular risk factors risk or not.</p> <p><strong>Results:</strong> A significant association with four factors were likely found to act as CVD predictors among adolescents like limited knowledge on prevention (AOR = 0.519, 95% CI = 0.358-0.752); inadequate information on diseases severity (AOR = 0.444, 95% CI = 0.284-0.696); low ability to promote health (AOR = 0.447, 95% CI = 0.295-0.677); and, non-confidence in practicing a healthy lifestyle (AOR = 0.584, 95% CI = 0.407-0.839).</p> <p><strong>Conclusion:</strong> Curriculum school inclusion of positive health practice might help much in improving the perceiveness on cardiovascular disease and better awareness in the coming generation.</p> Sayer Ofyer Al Ruwili, Amen Bawazir ##submission.copyrightStatement## Tue, 11 Aug 2020 00:00:00 +0000